Archive for the ‘biotechnology’ Category

Safety of Workers in Biotech Labs Tuesday, August 24th, 2010

In a recent blog post, the Council for Responsible Genetics has listed several shocking cases of workers in biotech labs contracting illnesses apparently related to their work, and yet being denied compensation in a timely manner.

A scientist who worked for Pfizer developing genetic delivery systems for cloning into viruses fell ill, and was sacked by the company when she could not return to work by the deadline date. She had to wage a struggle for several years before she was awarded compensation, and that too not for the illness but for the company violating her free speech and whistleblower rights.

It appeared that Pfizer could legally deny data on workers’ lab exposures, as it is protected as a trade secret.

Another person who worked as a researcher and technician on crop and insect control projects was exposed to living bacteria, fungi and insects, which he claims sickened him. He could not get any compensation due in no small measure to his employer providing him with the wrong name of its insurer. When finally he found the actual insurer, the latter also denied the claim.

The fact is that many of the microorganisms the researcher worked with were found in his body.

Read about these and other cases at CRG Blog.

The Ninth Biotechnology Industry Organization Investor Forum Saturday, August 21st, 2010

The Biotechnology Industry Organization (BIO) Investor Forum is a national investor conference held in the US. Participants of the forum include leading private and emerging public biotech companies, venture and private equity investors in healthcare, and investors interested in buying or selling. Business development executives from leading pharmaceutical and biotech companies participating in the forum will have the opportunity for networking and exploring for the kinds of deals they are looking for.

At this year’s conference, Chairman/CEO of Advaxis Inc., a biotechnology company developing proprietary, live, attenuated Listeria monocytogenes (Listeria) vaccines that deliver engineered tumor antigens, will discuss recent developments in the areas of clinical trials and financing.

Other topics slated to be discussed include:
– First patient group dosing in US-based, Phase II cervical dysplasia (CIN) trial

– Drug Controller General of India (DCGI) clearance to proceed with a India-based, Phase II cervical cancer trial

– National Cancer Institute — Gynecologic Oncology Group’s trial in cervix cancer

– CRUK trial in Head and Neck cancer

– Collaborative research and development agreement (CRADA) signing with the Department of Homeland Security (DHS) to study Listeria in animals

– $7.5 million in financing agreement with life science fund

Read the news release at Market Watch.

Scientific Development in Your Community: How do you Help? Wednesday, August 18th, 2010

Illinois Biotechnology Industry Organization’s stated objective is to “to make Illinois and the surrounding Midwest one of the world’s top life sciences center.” The organization makes annual iBIO Institute iCON Awards to “celebrate the accomplishments of outstanding science teachers and researchers whose work provides the basis for biotechnology developments worldwide.”

The fourth annual awards recipients of 2010 illustrate the kinds of contributions individuals can make to their community in the area of scientific development.

The Innovator Award (University Level) winner this year is Dr Brenda Russell, Ph.D., Professor of Physiology, Biophysics, Bioengineering and Medicine, and Executive Associate Vice Chancellor for Research at the University of Illinois at Chicago. Dr Russell has:

* spent several years guiding some of the brightest and most highly motivated research students in the state
* chaired several cross-disciplinary task forces at UIC including regenerative medicine with stem cells, environmental science, tobacco-related research (prevention psychology, clinical treatment and more), bioinformatics and structural biology
* lectured in the iBIO Institute’s TalentSparks! teacher development program and iBIO IndEx conferences
* lent her talent to Chicago’s Science in the City community outreach efforts

The Knowledge Builder Award (Grades 6-12) winner this year is Elizabeth Babcock, Ph.D., Vice President, Education and Library Collections at The Field Museum in Chicago. Dr Babcock:

* is responsible for the development and implementation of education programs, outreach initiatives and digital programming to over 800,000 adults, families, teachers and students each year
* helps improve the public’s understanding of natural history and to serve diverse audiences by leveraging the Museum’s exhibitions, collections and scientific research
* focuses on increasing the public’s access to and utilization of the Museum’s rare book collection, photo and institutional archives, and general collection of over 300,000 items

StockNod.

Market Reports on Biochips, Stem Cell Research and more Monday, August 16th, 2010

Market Publishers Ltd has just announced release of new market reports on drugs and biotechnology. The new reports cover Biochips, Stem Cell Research, Prions, Intravenous Solutions and Bionanotechnology.

Biochips: Biochips is a major thrust area under biotechnology along with such areas as genomics, protenomics and pharmaceuticals. Combining the understanding of cell functioning gained from the latter studies and the advanced micro-miniaturization capabilities of the semiconductor industry, one can develop biochips that act as sensors inside the body, where they can perform even thousands of biochemical reactions. Biochips have applications in various fields including disease diagnosis to detection of bioterrorism agents.

Stem Cell Research: Stem cells are cells in the body that can renew themselves through miotic cell division and grow into specialized cell types. Such specialized cells can help repair damaged organs by replenishing dead cells, for example. Embryonic stem cells can differentiate into cells of all the embryonic tissues while adult stem cells are more specialized. Bone marrow transplant is an example of adult stem cell therapy. Researchers hope to treat diseases like cancer, Parkinson’s, and more using stem cell therapy in the future.

The above and other market reports from the publishers provide the type of information that prospective entrepreneurs need.

Read the news release at Market Publishers Website.

Bt Brinjal and the GM Crops Dilemma Wednesday, August 11th, 2010

The Indian government has put an indefinite moratorium on the commercial release of genetically modified Bt Brinjal (egg plant). The moratorium was imposed in response to a situation where “there is no clear consensus within the scientific community itself, when there is so much opposition from the state governments, civil society organizations and eminent scientists have raised many serious questions not been answered satisfactorily,” according to the central government minister.

Critics of Bt Brinjal argue that the new engineered crop could destroy the vast bio-diversity of the numerous varieties of local brinjal. Preserving bio-diversity is critical because many of the genetic traits of the different varieties could prove invaluable. For example, new high-yielding varieties of rice that led to the Indian green revolution made governments neglect several local rice varieties that had traits like drought-resistance (though not high yields).

On the other hand, opponents of the moratorium point out that with the “uncertainty prevailing about GM crops, the companies wanting to invest in bio technology in agricultural sector would be hesitant to do so.” They complain that “there has been no palpable, effective and time bound effort to resolve the uncertainties caused by the moratorium.”

The case is an excellent example of the dilemma caused by GM crops with fears such as destruction of bio-diversity and unknown risks on one part and the risk of losing the benefits of scientific research on the other.

Read the news at Financial Express.

Biotechnology Industry Issues Wednesday, August 4th, 2010

The 2011 Call for Session Proposals – Educational Track released by convention.bio.org gives an insight into the issues facing the biotech industry.

The impact of regulatory and compliance requirements on the ability of the biotechnology industry to research and develop healthcare products is one major issue. In addition to R&D, marketing is also affected by regulations, not only of FDA of the U.S. but also of regulatory bodies in other countries.

Developing eco-friendly alternative solutions, in the forms of new materials and cleaner manufacturing processes is another issue. Bio-based products from biomass, biofuels and food ingredients are examples and the issues involved with each of these solutions need to be explored in detail. For example, the once promising biofuel is facing criticism on the ground that it reduces the availability of food crops in a world where a large number of people do not get adequate food.

Detection, prevention, diagnosis and treatment of diseases are helped by developing, validating and qualifying biological markers. Personalized medicine that decides the best treatment for each individual based on the person’s genetic characteristics is another area of major significance.

Intellectual property protection, global biotech licensing, technology transfer, and collaborations is another key issue for the industry. So is a clear picture of emerging trends in business development through partnering and alliances.

Read more by downloading the document from convention.bio.org website.

A Compact but Comprehensive Look at Biotechnology Sunday, July 25th, 2010

Do you know that biotechnology started quite early with such developments as producing wine by fermenting fruit juices and conversion of milk into cheese and yoghurt? These and other topics of interest to those wondering about the potential of biotechnology constitute the editorial content at volume 13 of Redalyc.

The compact piece points out that modern biotechnology started with the ability to transfer a specific gene from one organism to another, using genetic engineering techniques. Known as recombinant DNA technology, this development started the biotech revolution. The biotechnology revolution provided us with applications in disease prevention and treatment, among many others.

One important development is personalized medicine, which involves tailoring treatment to the genetic characteristics of the individual patient. Personalized medicine recognizes the fact that a person’s genetic make up can determine whether a particular treatment is effective for that person or not. It has been observed that the same treatment does not work for all people even when the disease being treated is the same.

The editorial also mentions about the widely varied degree of biotechnology research and development in developed countries like the U.S. and developing countries like Colombia. It observes that the developing countries are forced to use the products developed in advanced countries instead being able to develop products of their own.

The document can be downloaded from Redalyc.org website.

Biotechnology: What is its real Significance? Saturday, July 24th, 2010

Biotechnology is attracting attention in more and more countries with research facilities being set up in universities and other institutions in developing countries as well as developed nations. What exactly is its significance? What contributions has the industry made? What is its future potential?

A recent report from BIO, the Biotechnology Industry Organization, titled “Healing, Fueling, Feeding: How Biotechnology is Enriching Your Life” seeks to answer these questions. The intro page of the report starts with some great statistics:

* reduce CO2 emissions annually by 32 million tons simply by lowering the temperature of washing clothes and dishes
* protect 241 million people worldwide from malaria
* ensure no child ever goes hungry
* stop chronic diseases from causing seven out of every ten deaths every year

The biotechnology industry believes that it can meet these and other goals that thinking people consider as absolutely essential to create a world that is a better place to live, compared to the planet that we live in now. Biotechnology has already created many “breakthrough products and technologies to combat disease, reduce our environmental footprint, feed the hungry, and make useful products.” Most of us are not even aware of the many biotech applications we see in our homes and workplaces.

Learn how the ability of biotechnology to work with cellular and molecular processes are changing everything from the Value of Biotechnology Report.

Biotechnology in Vietnam Friday, July 23rd, 2010

Vietnam has developed demonstrated skill base in electronics, computing and software and has been able to attract both domestic and overseas investments in these fields. Not so well known is the biotechnology research in the country. Vietnam has recognized that biotechnology can help the country improve healthcare, as demonstrated by the biotech remedies developed in technologically advanced countries for hemophilia and detection of genetic diseases.

Developing countries like Vietnam face health problems such as increasing incidence of chronic diseases like diabetes and cancer, organisms that cause TB and malaria that acquire increasing resistance to conventional drugs, and outbreaks of infectious diseases like the flu. Biotechnology can help in this context by developing better preventive, diagnostic and treatment tools.

Researchers at the University of Medicine and Pharmacy in Ho Chi Minh City had conducted a series of polymerase chain reaction (PCR) experiments starting mid 1990s. PCR is a DNA-based diagnostic method for quickly and accurately detecting pathogens and its use has expanded rapidly since then. It is being used widely in Vietnam now to detect various local influenza viruses, and diagnosing malaria and multidrug-resistant tuberculosis.

Well equipped biotechnology research facilities, such as the Institute of Biotechnology and the Military Medical University in Hanoi with microarrays, high-resolution electron microscopes and mass spectrometers, are being established in the country. These institutions are able to carry the research into fields other than PCRs.

Read the report of one top researcher in Vietnam at SciDev.net.

Biotechnology Applications in the Textile Industry Tuesday, July 20th, 2010

Biotechnology improves crops by tailoring their properties or transferring properties from one organism to another. Both these processes involve working with the organisms’ genes (that determine genetic characteristics), made possible by advances in genetic engineering.

Genetic engineering has already benefited the textile industry and promises much more. For example, cotton, which is the leading fiber used by the textile industry, is vulnerable to attacks by many insects. Cotton also has poor tolerance against herbicides used to kill weeds in irrigated cotton fields. By working with the genes of the crop, scientists are hoping to develop insect and herbicide resistant varieties of cotton.

Another objective is to develop cotton varieties that will be naturally colored, say blue or vivid red, so that bleaching and dyeing of textiles can be eliminated. Research is also going on to provide other desirable properties at a genetic level.

In Australia, sheep is being “engineered” to secrete an insect repellant from its hair follicles to resist attacks from blowfly, and also stop hair growth so that wool can be “pulled off” instead of being sheared. Shearing wool from sheep is a cumbersome and time-consuming process.

Biotechnology is helping not only such genetic engineering results but is also helping in disease diagnostics and new forms of therapy, for example.

Read the great post on biotechnology applications in textile industry at The World of Snark.