A study of Rhesus monkeys shows that if a mother had an influenza attack while pregnant, its babies were born with smaller brains and other brain changes associated with Schizophrenia in humans. Earlier studies with mice has also indicated such a relationship.
In the study, even a relatively mild flu infection had a significant impact on the brains of the babies. While such a relationship has not been confirmed in humans, it is a good idea for pregnant women to take flu shots to prevent flu attacks during pregnancy.
The study involved infecting pregnant macaque monkeys with a mild flu virus one month before their babies were due. There was a control group of other pregnant monkeys who were not infected.
MRI scans of the brains of babies one year after birth showed no signs of direct viral attack, and no significant difference in birth weight, gestation length and different responses.
However, significant reductions were noticed in brain sizes, and the gray and white matter in specific areas of the brain of the babies born to flu infected mothers. These were changes that are typical in the MRI scans of Schizophrenia patients.
Read the details of the study at: ScienceBlog.
